CorInnova, Inc.

JLABS @ TMC

2450 Holcombe Blvd. Suite J

Houston, Texas 77021

Phone: (346) 772-0345

Email: info@corinnova.com

© 2018 CorInnova. All Rights Reserved.

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Mechanism of Action

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By utilizing a less invasive implantation procedure and a less invasive non-blood contacting device, EpicHeartTM is designed to eliminate up to 40% of the adverse events associated with LVADs - stroke, thrombus, gastrointestinal bleeding, and right heart failure. CorInnova’s  EpicHeartTM is designed to expand patient eligibility up to 280,000 patients (28%), potentially providing longer life and higher quality of life due to anticipated shorter hospital stays (6 days vs. 20 to 35 days) and reduced adverse events/re-hospitalizations.  Moreover, EpicHeartTM should lead to cardiac restoration in much greater frequency than LVADs (1 to 2 1/2%) by correcting motion, reducing wall stress, and normalizing cytokine signaling – key factors in restorative cardiac remodeling.